Senior Director of Manufacturing

Piper Companies is seeking a Sr. Director of Manufacturing for a leading global CDMO located in Durham, North Carolina (NC). The Sr. Director of Manufacturing will be responsible for overseeing large-scale GMP manufacturing operations, ensuring compliance with regulatory standards, and driving operational excellence across multiple production lines. This is a hybrid position in Durham, NC.

Responsibilities of the Sr. Director of Manufacturing:

• Lead all GMP manufacturing operations, including production planning, scheduling, and execution.
• Ensure compliance with cGMP, FDA, and global regulatory standards across all processes.
• Drive continuous improvement initiatives to enhance efficiency, reduce costs, and maintain quality.
• Partner with Quality, Supply Chain, and Engineering to achieve production and client goals.
• Mentor and develop manufacturing leadership teams, promoting a culture of safety and compliance.
• Oversee technology transfer, scale-up, and validation for new products and processes.
• Monitor KPIs and deliver performance reports to senior leadership for strategic decision-making.

Qualifications for the Sr. Director of Manufacturing:

• 10+ years of experience in pharmaceutical or biologics manufacturing, with at least 5 years in a leadership role.
• Strong background and knowledge of aseptic processing, biologics, or sterile drug product manufacturing.
• Proven track record in managing large teams and complex manufacturing operations.
• Experience in a CDMO environment highly preferred.

Compensation for the Sr. Director of Manufacturing:

• Salary Range: Starting at $200,000/year

This job opens for applications on 11/12/2025. Applications for this job will be accepted for at least 30 days from the posting date.

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