Downstream CQV Engineer

Piper Companies is seeking a Downstream CQV Engineer to join a growing organization within the life sciences and biopharmaceutical manufacturing industry for an onsite 6-month contract with extensions based out of Holly Springs, NC. This Downstream CQV Engineer role supports large‑scale manufacturing operations, with a strong focus on downstream systems, utilities, and equipment commissioning and qualification activities in a multi‑building production environment.

Responsibilities of the Downstream CQV Engineer include:

· Execute commissioning, qualification, and verification activities for downstream manufacturing systems and utilities.

· Support installation verification and field execution by reviewing drawings, P&IDs, and system documentation.

· Perform hands‑on testing, troubleshooting, and walkdowns of large‑scale equipment including pumps, filters, valves, and piping networks.

· Partner with engineering, operations, and quality teams to resolve issues and maintain project timelines across multiple manufacturing suites.

· Contribute to electronic documentation and turnover packages, ensuring compliance with internal and regulatory expectations.

Qualifications for the Downstream CQV Engineer include:

· 2–10 years of hands‑on experience in CQV, validation, or engineering within large‑scale manufacturing environments.

· Practical experience with downstream processing equipment; ultrafiltration exposure is strongly preferred.

· Mechanical or engineering‑focused background with the ability to disassemble, inspect, and troubleshoot equipment and instrumentation.

· Familiarity with installation verification, utilities qualification, and system turnover activities.

· Experience with electronic validation systems such as Kneat is preferred but not required.

Compensation for the Downstream CQV Engineer:

Salary Range: $85,000-$100,000/year (USD)

Comprehensive Benefits: Medical, Dental, Vision, sick leave if required by law, and 401K

This job opens for applications on 5/20/26. Applications for this job will be accepted for at least 30 days from the posting date.

Keywords: CQV engineer, commissioning, qualification, validation, downstream processing, ultrafiltration, IV, P&IDs, utilities qualification, large scale manufacturing, biopharmaceuticals, GMP, mechanical engineering, process equipment, pumps, filters, valves, Kneat, system turnover, field execution, equipment qualification, biotech manufacturing, water systems, UF systems.

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