Senior Clinical Operations Manager - 176106

Piper Companies is seeking a Senior Clinical Project Manager to join a leading clinical research and healthcare organization for a fully remote permanent position. The Senior Clinical Project Manager will oversee global clinical development programs, driving study execution, timeline adherence, and operational success across complex Internal Medicine trials, with a strong focus on cardiometabolic indications.

Responsibilities of the Senior Clinical Project Manager include:

· Direct global clinical trial programs from study startup through closeout, ensuring deliverables, budgets, and timelines remain on track.

· Lead cross-functional teams, external vendors, and key stakeholders to support successful execution of clinical studies across multiple regions.

· Manage project risks, resources, forecasts, and operational challenges while maintaining high standards of quality and compliance.

· Oversee studies within cardiometabolic therapeutic areas, including MASH, obesity, diabetes, and cardiovascular research programs.

· Provide strategic leadership, mentorship, and guidance to project teams while driving process enhancements and operational excellence initiatives.

Qualifications for the Senior Clinical Project Manager include:

· Bachelor’s degree in Life Sciences, Business Administration, Project Management, or a related field; advanced degree preferred.

· Extensive clinical project management experience within a pharmaceutical, biotechnology, or contract research organization environment.

· Proven success managing global clinical trials, including experience within cardiometabolic indications such as MASH, obesity, diabetes, and cardiovascular studies.

· Strong understanding of clinical development processes, project management methodologies, GCP, ICH guidelines, and regulatory requirements.

· Excellent leadership, communication, problem-solving, and organizational skills with the ability to manage multiple priorities in a fast-paced environment.

Compensation for the Senior Clinical Project Manager:

Salary Range: $165,000-$175,000/year (USD)

Comprehensive Benefits: Medical, Dental, Vision, sick leave if required by law, and 401K

This job opens for applications on 10/2/26. Applications for this job will be accepted for at least 30 days from the posting date.

Keywords: senior clinical project manager, clinical project management, global clinical trials, clinical research, CRO, pharmaceutical industry, biotechnology, internal medicine, cardiometabolic, MASH, metabolic dysfunction-associated steatohepatitis, obesity, diabetes, cardiovascular studies, clinical operations, study management, project planning, risk management, budget management, vendor oversight, stakeholder engagement, clinical development, ICH, GCP, regulatory compliance, forecasting, resource management, trial execution, study startup, cross-functional leadership, clinical programs, project delivery, operational excellence, strategic planning, clinical trial oversight, lifecycle management.

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